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3,5-Diiodothyronine, also known as T2 is an active thyroid hormone. People take 3,5-T2 to lose weight, treat high cholesterol, and enhance bodybuilding.

How does 3,5-Diiodothyronine Work in supplements?

Some animal and test tube research suggests that diiodothyronine might speed up metabolism and reduce fat storage. T2 is a supplement designed to stimulate the thyroid gland,” and therefore “up” your metabolic rate. It may also have a positive effect on insulin resistance and hunger.

Studies on T2

In a study addressing T2’s ability to burn fat it was seen that T2 decreased stored fat of rats fed with a high fat diet (*in a caloric surplus*) by 13% while the rats fed the same diet without T2 gained 13% mass, all fat. The control group had a normal diet (*maintenance calories*) and did not change in total body mass, fat or otherwise.

Notable from this study, aside from the fact that T2 blatantly turbo charged fat loss in the rats that took it, it showed that T2 use for a month straight literally had ZERO negative effect on TSH (thyroid stimulating hormone), Thyroid Releasing Hormone (TRH), heart size, heart rate, or any other cause for concern.

Most impressively, lean muscle mass was left completely intact in the T2 testing group, which is substantially different than studies performed on T3 (triiodothyronine) which have proven T3’s blatant propensity to eat up muscle mass.

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